Drug Manufacturers - General · NASDAQ
Current Price
$146.12
Intrinsic Value
$166.43
+12.2% margin of safety
As of 2026-08-21, the base-case DCF model estimates the intrinsic value of Gilead Sciences, Inc. (GILD) at $166.43 per share, compared with a market price of $146.12, a margin of safety of +12.2%. The base case assumes 5.6% annual free cash flow growth and a 10.0% discount rate.
Across the sensitivity grid the estimate spans $129.34 to $209.43. Intrinsic value is an estimate built on assumptions, not a fact. A higher discount rate or slower growth pushes the estimate down, while stronger cash flow growth lifts it.
How the DCF works · Recalculate with your own assumptions · What is intrinsic value?
At $146.12, GILD trades about 12.2% below the base-case intrinsic value estimate. That is a real discount, but it stays short of the 30% margin of safety required before calling a stock undervalued.
COMPETITIVE MOAT
↑Dominant HIV Franchise
Gilead's long-standing leadership in HIV treatment, with drugs like Biktarvy, creates significant patient and physician loyalty. This established market position is difficult for competitors to dislodge.
↑Strong Oncology Pipeline
Investments in oncology, including recent advancements, offer potential for future blockbuster drugs. This diversification reduces reliance on any single therapeutic area.
↑Patented Drug Portfolio
Gilead holds patents on key revenue-generating drugs, providing a period of exclusivity and pricing power. This protects its market share from generic competition.
INVESTMENT RISKS
↓Clinical Trial Failures
The success of pharmaceutical companies hinges on the outcomes of clinical trials. A failure in a key drug development program could significantly impact future revenue.
↓Competition in Oncology
The oncology market is highly competitive with numerous players investing heavily in research and development. New entrants or breakthroughs could challenge Gilead's position.
↓Integration of Acquisitions
While acquisitions can bolster the pipeline, integrating new assets and realizing synergies can be challenging. Poor integration could lead to underperformance.
Base case
Intrinsic Value
$166.43
Margin of safety
+12.2%
Expected annual return
+2.6%
Base case assumptions: 5.6% annual growth, 10.0% discount rate, 13.74x exit multiple, 5 year projection. Data as of 2026-08-21.
This base case uses default assumptions and is not financial advice. The intrinsic value changes significantly when the growth rate or discount rate changes. Open the calculator to set your own assumptions and see the full sensitivity range.
Adjust the growth rate, discount rate, and exit multiple to see how the intrinsic value and margin of safety for Gilead Sciences, Inc. respond.
Open DCF Calculator for GILDGilead Sciences, Inc. is a global biopharmaceutical enterprise, with operations spanning the United States, Europe, and numerous international markets. Its core mission involves discovering, developing, and commercializing innovative medications to address critical health needs. The company's extensive product portfolio encompasses treatments for a variety of severe conditions. For HIV/AIDS, it supplies key therapies such as Biktarvy, Genvoya, Descovy, Odefsey, Truvada, Complera/Eviplera, Stribild, and Atripla. In response to the 2019 coronavirus pandemic, Gilead provides Veklury, an injectable drug for intravenous administration. Its offerings for liver diseases include Epclusa, Harvoni, Vosevi, Vemlidy, and Viread. Furthermore, Gilead assists patients battling hematological disorders, various cancers, and those undergoing cell therapy, through products like Yescarta, Tecartus, Trodelvy, and Zydelig. Other specialized medicines include Letairis, an oral drug for pulmonary arterial hypertension; Ranexa, also an oral medication, for chronic angina; and AmBisome, a liposomal formulation designed to combat serious invasive fungal infections. Gilead Sciences, Inc. actively engages in collaboration agreements with a diverse range of partners to advance its therapeutic pipeline. These include Arcus Biosciences, Inc., Pionyr Immunotherapeutics Inc., Tizona Therapeutics, Inc., Tango Therapeutics, Inc., Jounce Therapeutics, Inc., Galapagos NV, Janssen Sciences Ireland Unlimited Company, Japan Tobacco, Inc., Gadeta B.V., Bristol-Myers Squibb Company, Dragonfly Therapeutics, Inc., and Merck & Co, Inc. The company was founded in 1987 and its corporate headquarters are situated in Foster City, California.
Revenue/Share (TTM)
$24.50
FCF/Share (TTM)
$10.62
ROIC (TTM)
-3.7%
ROE (TTM)
-16.3%
P/FCF
13.7x
EV/EBITDA
321.5x
FCF Yield
7.28%
Debt/Equity
2.22x
Based on trailing twelve-month data, GILD shows a free cash flow per share of $10.62 and a ROIC of -3.7%, key inputs for stock valuation using the DCF method. The P/FCF ratio of 13.7x and FCF yield of 7.28% are important context metrics when evaluating GILD's stock valuation relative to peers.
Gilead Sciences, Inc. currently generates $10.62 in free cash flow per share. At the current price of $146.12, a DCF model would discount these cash flows at an appropriate WACC and apply a terminal growth rate to arrive at an intrinsic value. The result depends heavily on your growth and discount rate assumptions — a 1% change in WACC typically shifts the fair value estimate by 10-15%. In MiniValuator the model uses a single discount rate that you can edit directly, 10% by default, rather than a computed WACC.
GILD trades at a P/FCF ratio of 13.7x with a free cash flow yield of 7.28%. A low P/FCF means investors are paying less per dollar of free cash flow; whether that is cheap depends on the company's growth, cyclicality, and capital intensity. However, whether GILD is truly undervalued requires comparing the DCF intrinsic value to the current market price and evaluating whether the margin of safety is sufficient for your risk tolerance.
To perform a DCF valuation on Gilead Sciences, Inc.: (1) Start with the trailing free cash flow per share ($10.62) as the base, (2) project future FCF growth over 5-10 years based on Drug Manufacturers - General industry trends and company fundamentals, (3) apply a discount rate (WACC) reflecting GILD's risk profile — with a debt-to-equity of 2.22x, capital structure is an important factor, and (4) add a terminal value for cash flows beyond the projection period.
DCF (Discounted Cash Flow) estimates what a company is worth today based on its future cash generation. For Gilead Sciences, Inc., this means projecting how much free cash flow the company will produce over the next 5-10 years, shaped by Drug Manufacturers - General trends, then discounting those amounts to today's dollars. GILD's ROIC of -3.7% means the company's return on invested capital sits below the level that typically clears its cost of capital.
WACC (Weighted Average Cost of Capital) is the discount rate in a DCF model — it reflects the minimum return investors require. For GILD, with a debt-to-equity ratio of 2.22x, the capital structure directly influences WACC. A 1% increase in WACC typically reduces the intrinsic value by 10-15%. At an EV/EBITDA of 321.5x, the market's implied discount rate can be reverse-engineered for comparison. In MiniValuator you set this discount rate yourself as a single editable number, 10% by default, instead of computing a formal WACC.
DCF and P/E value GILD with different methods and assumptions, so the two conclusions can differ. Compare the P/E fair value.
Price as of 2026-08-21. Financial data from Financial Modeling Prep (trailing twelve months) · Valuation methodology by Charlie Wang.
This is an estimate, not investment advice.