Medical - Instruments & Supplies · NASDAQ
Current Price
$353.10
PE Ratio (TTM)
39.9x
Intrinsic Value
$441.27
+20.0% margin of safety
As of 2026-07-29, applying a 40.0x earnings multiple to Intuitive Surgical, Inc.'s (ISRG) earnings per share of $8.85 yields a fair value estimate of $441.27 per share, versus a market price of $353.1.
Fair value from earnings multiples is sensitive to the multiple you choose. Across the sensitivity grid the estimate spans $377.92 to $512.5. This is a relative estimate anchored to earnings, not a statement of fact. For a cash flow based view, see the intrinsic value estimate on the DCF page.
How the PE model works · Recalculate in PE mode · ISRG intrinsic value (DCF view)
At $353.1, ISRG trades about 20.0% below its PE-based fair value estimate, a modest discount to its earnings power, though not enough to call it cheap outright.
COMPETITIVE MOAT
↑Robotic Surgery Pioneer
Intuitive Surgical's early entry and sustained innovation in robotic-assisted surgery created a significant first-mover advantage. This established them as the dominant player in a nascent market.
↑Surgeon Training & Ecosystem
Extensive surgeon training programs and a proprietary ecosystem of instruments and accessories create high switching costs for hospitals and surgeons. This deep integration fosters loyalty.
↑Data & Performance Insights
The vast amount of data collected from da Vinci system procedures provides unique insights for product development and performance optimization. This scale advantage is difficult for competitors to replicate.
INVESTMENT RISKS
↓Valuation Concerns
The company's premium valuation, as highlighted by comparisons to competitors like Stryker, could make it susceptible to significant price corrections if growth expectations are not met.
↓Regulatory Scrutiny
As a leader in a critical medical field, Intuitive Surgical faces ongoing regulatory oversight and potential changes in approval processes for new devices and procedures.
↓Diversification vs. Specialization
Unlike more diversified healthcare companies like Abbott Laboratories, ISRG's focus on robotic surgery makes it more vulnerable to sector-specific headwinds or shifts in surgical trends.
Base case
Intrinsic Value
$441.27
Margin of safety
+20.0%
Expected annual return
+4.6%
Base case assumptions: 12.4% annual earnings growth, 40x target PE, 10% discount rate, 5 year projection. Data as of 2026-07-29.
This base case uses default assumptions and is not financial advice. The fair value changes significantly when the target PE or earnings growth rate changes. Open the calculator to set your own assumptions and see the full sensitivity range.
Adjust the target PE, earnings growth, and discount rate to see how the fair value and margin of safety for Intuitive Surgical, Inc. respond.
Open PE Calculator for ISRGIntuitive Surgical, Inc. is a leading medical technology firm dedicated to advancing patient care by developing, producing, and commercializing sophisticated tools. These innovations empower medical professionals to deliver superior, accessible, and less-invasive treatment options to patients both within the United States and across international markets. Its flagship offering, the da Vinci Surgical System, facilitates intricate operations through a minimally disruptive approach. Expanding beyond surgical applications, the company also provides the Ion endoluminal system, designed for diagnostic interventions like minimally invasive lung biopsies. Complementing its primary systems, Intuitive Surgical supplies a comprehensive array of instruments, including stapling tools, energy devices, and essential core components. Furthermore, it offers structured training programs to ensure proficient use of its technology, alongside extensive customer support services encompassing installation, repairs, and ongoing maintenance. The firm also integrates digital capabilities to deliver unified, connected solutions that optimize hospital performance through actionable insights. Established in 1995, Intuitive Surgical maintains its corporate headquarters in Sunnyvale, California.
PE Ratio (TTM)
39.9x
PEG Ratio
1.88
Earnings Yield
2.51%
ROE (TTM)
17.8%
Revenue/Share (TTM)
$31.13
The trailing twelve-month PE ratio of ISRG reflects how much investors pay per dollar of Intuitive Surgical, Inc.'s earnings. This metric is most useful when compared to Medical - Instruments & Supplies peers and the company's own historical range.
ISRG's PE of 39.9x combined with a PEG ratio of 1.88 provides a growth-adjusted perspective. A PEG near 1.0 means the P/E is roughly in line with the earnings growth rate. Keep in mind that PE-based valuation works best for profitable, mature companies — for high-growth or cyclical Medical - Instruments & Supplies, a DCF analysis may be more appropriate.
To value Intuitive Surgical, Inc. using PE: (1) Compare the current PE (39.9x) against the Medical - Instruments & Supplies median to assess relative pricing, (2) check the PEG ratio (1.88) to adjust for growth expectations, (3) review the 5-year PE range to identify where the stock sits historically, and (4) estimate fair value by multiplying a target PE by forward EPS estimates. This relative approach complements DCF's absolute valuation.
ISRG's PEG ratio is 1.88, calculated by dividing the PE ratio (39.9x) by the expected earnings growth rate. A PEG near 1.0 means the P/E is roughly in line with the expected earnings growth rate. Note that PEG accuracy depends on the reliability of growth estimates.
PE ratio gives a quick relative read — how ISRG is priced versus Medical - Instruments & Supplies peers. DCF provides an absolute value based on projected free cash flows. For ISRG, with a strong ROE of 17.8%, both methods are worth using — PE for a market-relative check, DCF to stress-test whether fundamentals justify the price. Each method has blind spots: PE ignores capital structure and cash flow quality, while DCF is sensitive to growth and discount rate assumptions.
P/E and DCF value ISRG with different methods and assumptions, so the two conclusions can differ. Compare the DCF intrinsic value.
Price as of 2026-07-29. Financial data from Financial Modeling Prep (trailing twelve months) · Valuation methodology by Charlie Wang.
This is an estimate, not investment advice.